How To Clean Night Guard With Vinegar. Then, rinse your night guard and soak it in hydrogen peroxide for 30 minutes. You should let this sit for at least three to five hours, but overnight is best.
First, soak your night guard in white vinegar for 30 minutes. Allow it to soak for at least 10 minutes and up to 30 minutes. Do the same for the glass or bowl that you used.
You don't have to be concerned with rinsing it afterward, because white vinegar is not toxic.
After soaking, remove the night guard and rinse it with water. The denture tabs did nothing, and it was tedious to brush it with baking soda. Rinse your mouth guard or night guard under lukewarm tap water. Hydrogen peroxide and white vinegar.